Characterization through scanning electron microscopy and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>μ</mml:mi></mml:math>Fourier transform infrared spectroscopy of microcalcifications present in fine needle aspiration smears
نویسندگان
چکیده
In this contribution, we have characterized for the first time (to best of our knowledge), microcalcifications present in fine needle aspiration (FNA) smears thyroid nodules. Abnormal deposits were analysed through μFourier Transform Infrared Spectroscopy (μFTIR) and Field Emission Scanning Electron Microscopy (FE-SEM) order to obtain their chemical composition as well morphology at micrometer scale. Thirty-one samples coming from 13 patients investigated comprising five cases papillary carcinoma, two Graves’ disease, six adenomatous goitre. The also stained analysis cellular characteristics these lesions classifying according Bethesda classification. Two mineral species, amorphous nanocrystallised apatite calcium phosphate, been identified with very different morphologies. Moreover, FE-SEM observations scale underline presence kinds abnormal deposits. Dans cette nous avons caractérisé pour la première fois à notre connaissance, les présentes dans ponctions thyroïdiennes. Les dépôts anormaux ont été analysés par micro spectroscopie infrarouge transformée de Fourier et microscopie électronique balayage émission champ afin d’obtenir leur chimique ainsi que morphologie l’échelle micrométrique. Trente un échantillons provenant étudiés, dont 5 cas carcinome papillaire, 2 maladie Basedow 6 goitre adénomateux. également colorées analyser caractéristiques cellulaires ces lésions classer selon classification Bethesda. Deux espèces minérales, le phosphate amorphe nanocristallisé, identifiées avec des morphologies très différentes. De plus, micrométrique soulignent présence différents types anormaux.
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ژورنال
عنوان ژورنال: Comptes Rendus Chimie
سال: 2022
ISSN: ['1878-1543', '1631-0748']
DOI: https://doi.org/10.5802/crchim.187